137.Becht P., König J., Feldbrügge M. The RNA-binding protein Rrm4 is essential for polarity in Ustilago maydis and shuttles along microtubules // J. Cell Sci. 2006. V.119. P.4964–4973.
138.Been M.D., Perrotta A.T. Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site // Science. 1991. V.252. P.434–437.
139.Beigelman L., McSwiggen J.A., Draper K.G., Gonzalez C., Jensen K., Karpeisky A.M., Modak A.S., Matulic-Adamic J., DiRenzo A.B., Haeberli P., et al. Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance // J. Biol. Chem. 1995. V.270. P.25702-25708.
140.Bell C., Lynam E., Landfair D.J., Janjic N., Wiles M.E. Oligonucleotide NX1838 inhibits VEGF165-mediated cellular responses in vitro // In Vitro Cell Dev. Biol. Anim. 1999. V.35. P.533-542.
141.Berens C., Thain A., Schroeder R. A tetracycline-binding RNA aptamer // Bioorg. Med. Chem. 2001. V.9. P.2549–2556.
142.Berezovski M., Drabovich A., Krylova S.M., Musheev M., Okhonin V., Petrov A., Krylov S.N. Nonequilibrium capillary electrophoresis of equilibrium mixtures: a universal tool for development of aptamers // J. Am. Chem. Soc. 2005. V.127. P.31653171.
143.Berezovski M., Musheev M., Drabovich A., Krylov S.N. Non-SELEX selection of aptamers // J. Am. Chem. Soc. 2006. V.128. P.1410–1411.
144.Bergeron L.J., Perreault J.P. Target-dependent on/off switch increases ribozyme fidelity // Nucleic Acids Res. 2005. V.33. P.1240–1248.
145.Bergman N.H., Johnston W.K., Bartel D.P. Kinetic framework for ligation by an efficient RNA ligase ribozyme // Biochemistry. 2000. V.39. P.3115–3123.
146.Bernstein D.S., Buter N., Stumpf C., Wickens M. Analyzing mRNA-protein complexes using a yeast three-hybrid system // Methods. 2002. V.26. P.123–141.
147.Bernstein D., Hook B., Hajarnavis A., Opperman L., Wickens M. Binding specificity and mRNA targets of a C. elegans PUF protein, FBF-1 // RNA. 2005. V.11. P.447–458.
148.Bevilacqua P.C., Yajima R. Nucleobase catalysis in ribozyme mechanism // Curr. Opin. Chem. Biol. 2006. V.10. P.455-464.
86
149.Beyer S., Dittmer W.U., Simmel F.C. Design Variations for an Aptamer-Based DNA Nanodevice // Journal of Biomedical Nanotechnology. 2005. V.1. P.96–101.
150.Beyer S., Simmel F.C.A modular DNA signal translator for the controlled release of a protein by an aptamer // Nucleic Acids Research. 2006. V.34. P.1581–1587.
151.Bianchini M., Radrizzani M., Brocardo M.G., Reyes G.B., Solveyra C.G., Santa–
Coloma A. Specific oligobodies against ERK-2 that recognize both the native and the denatured state of the protein // J. Immunol. Methods. 2001. V.252. P.191-197.
152.Bieling P., Beringer M., Adio S., Rodnina M.V. Peptide bond formation does not involve acid-base catalysis by ribosomal residues // Nat. Struct. Mol. Biol. 2006. V.13. P.423-428.
153.Biesecker G., Dihel L., Enney K., Bendele R.A. Derivation of RNA aptamer inhibitors of human complement C5 // Immunopharmacology. 1999. V.42. P.219-230.
154.Binkley J., Allen P., Brown D.M., Green L., Tuerk C., Gold L. RNA ligands to human nerve growth factor // Nucleic Acids Res. 1995. V.23. P.3198-3205.
155.Birikh K.R., Heaton P.A., Eckstein F. // Eur. J. Biochem. 1997. V.245. P.1–16.
156.Biroccio A., Hamm J., Incitti I., De Francesco R., Tomei L. Selection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNAdependent RNA polymerase // J. Virol. 2002. V.76. P.3688–3696.
157.Bishop J.S., Guy-Caffey J.K., Ojwang J.O., Smith S.R., Hogan M.E., Cossum P.A., Rando R.F., Chaudhary N. Intramolecular G-quartet motifs confer nuclease resistance to a potent anti-HIV oligonucleotide // J. Biol. Chem.. 1996. V.271. P.5698–5703.
158.Blank M., Blind M. Aptamers as tools for target validation // Curr. Opin. Chem. Biol. 2005. V.9. P.336.
159.Blank M., Weinschenk T., Priemer M., Schluesener H. Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. Selective targeting of endothelial regulatory protein pigpen // J. Biol. Chem. 2001. V.276. P.16464-16468.
160.Blind M., Kolanus W., Famulok M. Cytoplasmic RNA modulators of an inside-out signal-transduction cascade // Proc. Natl. Acad. Sci. USA. 1999. V.96. P.3606-3610.
87
161.Blouin S., Lafontaine D.A. A loop–loop interaction and a K-turn motif located in the lysine aptamer domain are important for the riboswitch gene regulation control // RNA. 2007. V.13. P.1256-1267.
162.Bock L.C., Griffin L.C., Latham J.A., Vermaas E.H., Toole J.J. Selection of singlestranded DNA molecules that bind and inhibit human thrombin // Nature. 1992. V.355. P.564-566.
163.Boese B.J., Breaker R.R. In vitro selection and characterization of cellulosebinding DNA aptamers // Nucleic Acids Research. 2007. V.35. P.6378-6388.
164.Bogenhagen D.F., Brown D.D. Nucleotide sequences in Xenopus 5S DNA required for transcription termination // Cell. 1981. V.24. P.261–270.
165.Boiziau C., Dausse E., Mishra R., Duconge F., Toulme J.J. Identification of aptamers against the DNA template for in vitro transcription of the HIV-1 TAR element // Antisense Nucleic Acid Drug Dev. 1997. V.7. P.369-380.
166.Boiziau C., Dausse E., Yurchenko L., Toulme J.J. DNA aptamers selected against the HIV-1 trans-activation-responsive RNA element form RNA-DNA kissing complexes // J. Biol. Chem. 1999. V.274. P.12730–12737.
167.Bokman S.H., Ward W.W. Renaturation of Aequorea green-fluorescent protein // Biochem. Biophys. Res. Commun. 1981. V.101. P.1372-1380.
168.Bondensgaard K., Mollova E.T., Pardi A. The global conformation of the hammerhead ribozyme determined using residual dipolar couplings // Biochemistry. 2002. V.41. P.11532–11542.
169.Borer P.N. et al. // Biochemistry. 1995. V.34. P.6488.
170.Braasch D.A., Corey D.R. Locked nucleic acid (LNA): fine-tuning the recognition of DNA and RNA // Chem. Biol. 2000. V.55. P.1–7.
171.Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding // Anal. Biochem. 1976. V.72. P.248–254.
172.Breaker R.R. In Vitro Selection of Catalytic Polynucleotides // Chem. Rev. 1997. V.97. P.371-390.
173.Breaker R.R. Engineered allosteric ribozymes as biosensor components // Curr. Opin. Biotechnol. 2002. V.13. P.31–39.
88
174.Breaker R.R. DNA aptamers and DNA enzymes // Curr. Opin. Chem. Biol. 1997. V.1. P.26–31.
175.Breaker R.R. Riboswitches and the RNA World // The RNA World—Gesteland RF. Cech T.R., Atkins J.F., eds. 3rd. Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press, 2006.
176.Breaker R.R., Joyce G.F. Inventing and improving ribozyme function—rational design versus iterative selection methods // Trends Biotechnol. 1994. V.12. P.268–
275.
177.Breaker R.R., Joyce G.F. A DNA enzyme that cleaves RNA // Chem. Biol. 1994. V.1. P.223-229.
178.Breaker R.R., Joyce G.F. A DNA enzyme with Mg2+-dependent RNA phosphoesterase activity // Chem. Biol. 1995. V.2. P.655-660.
179.Bridonneau P., Chang Y.F., O'Connell D., Gill S.C., Snyder D.W., Johnson L., Goodson T., Jr., Herron D.K., Parma D.H. High-affinity aptamers selectively inhibit human nonpancreatic secretory phospholipase A2 (hnps-PLA2) // J. Med. Chem. 1998. V.41. P.778-786.
180.Brockstedt U., Uzarowska A., Montpetit A., Pfau W., Labuda D. In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines // Biochem. Biophys. Res. Commun. 2004. V.313. P.1004–1008.
181.Brody E.N., Gold L. Aptamers as therapeutic and diagnostic agents // J. Biotechnol. 2000. V.74. P.5–13.
182.Brody E.N., Willis M.C., Smith J.D., Jayasena S., Zichi D., Gold L. The use of aptamers in large arrays for molecular diagnostics // Mol. Diagn. 1999. V.4. P.381–
388.
183.Brooijmans N., Sharp K.A., Kuntz I.D. Stability of macro-molecular complexes // Proteins. 2002. V.48. P.645–653.
184.Bruesehoff P.J., Li J., Augustine A.J., 3rd, Lu Y. Improving metal ion specificity during in vitro selection of catalytic DNA // Comb. Chem. High Throughput Screen. 2002. V.5. P.327-335.
185.Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells // Science. 2002. V.296. P.550–553.
89
186.Bruno J.G., Kiel J.L. In vitro selection of DNA aptamers to anthrax spores with electrochemiluminescence detection // Biosens. Bioelectron. 1999. V.14. P.457-464.
187.Bryant K.F., Cox J.C., Wang H., Hogle J.M., Ellington A.D., Coen D.M. Binding of herpes simplex virus-1 US11 to specific RNA sequences // Nucleic Acids Res. 2005. V.33. P.6090-6100.
188.Buck J., Furtig B., Noeske J., Wohnert J., Schwalbe H. Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution // PNAS. 2007. V.104. P.15699–15704.
189.Bunka D.H.J., Mantle B.J., Morten I.J., Tennent G.A., Radford S.E., Stockley P.G. Production and Characterization of RNA Aptamers Specific for Amyloid Fibril Epitopes // J. Biol. Chem. 2007. V.282. P.34500-34509.
190.Bunka D.H.J., Stockley P.G. Aptamers come of age—at last! // Nat. Rev. Microbiol. 2006. V.44. P.589–596.
191.Burge S., Parkinson G.N., Hazel P., Todd A.K., Neidle S. Quadruplex DNA: sequence, topology and structure // Nucleic Acids Res. 2006. V.34. P.5402–5415.
192.Burgstaller P., Famulok M. Isolation of RNA–aptamers for biological cofactors by in vitro selection // Angew. Chem. Int. Ed. Engl. 1994. V.33. P.1084–1087.
193.Burgstaller P., Famulok M. Structural characterization of a flavin-specific RNA aptamer by chemical probing // Bioorg. Med. Chem. Lett. 1996. V.6. P.1157-1162.
194.Burgstaller P., Jenne A., Blind M. Aptamers and aptazymes: accelerating small molecule drug discovery // Curr. Opin. Drug. Discov. Devel. 2002. V.5. P.690–700.
195.Burgstaller P., Kochoyan M., Famulok M. Structural probing and damage selection of citrullineand arginine-specific RNA aptamers identify base positions required for binding // Nucleic Acids Res. 1995. V.23. P.4769-4776.
196.Burke D.H., Gold L. RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX // Nucleic Acids Res. 1997. V.25. P.2020–2024.
197.Burke D.H., Hoffman D.C. A novel acidophilic RNA motif that recognizes coenzyme A // Biochemistry. 1997. V.37. P.4653–4663.
90