Наше исследование показывает на ранее неизвестные факты высокой распространенности пищеводных манометрических нарушений у пациентов ХК, имеющих симптомы ГЭРБ. Нарушения моторики пищевода могут быть важными факторами патогенеза кашля у этих пациентов. Суточная рН-метрия и манометрия позволяют дифференцировать этих пациентов с общей популяцей больных с ХК, что, в свою очередь, существенно расширяет возможности оптимизации терапии.
Список литературы
1. Palombini B.C., Villanova C.A., Arao E., et al. A pathogenic triad in chronic cough: asthma, postnasal drip syndrome, and Gastroesophageal reflux disease. // Chest 1999. -Vol.116. -P.279-284.
2. Irwin R.S., Zawacki J.K., Curley F.J., et al. Chronic cough as the sole presenting manifestation of gastroesophageal reflux. // Am. Rev. Respir. Dis. - 1989. -Vol.140. -P.1294-1300.
3. Kahrilas P.J., Dodds WJ., Hogan W.J., et al. Esophageal peristaltic dysfunction in peptic esophagitis. // Gastroenterology. -1986. -Vol.91. -P.897-904.
4. Richter J.E., Wu W.C., Johns D.N., et al. Esophageal manometry in 95 healthy adult volunteers: variability of pressures with age and frequency of "abnormal" contractions. // Dig. Dis. Sci. - 1987. - Vol. 32. -P. 583-592.
5. Kahrilas P.J., Clouse R.E., Hogan W.J. American Gastroenterological Association technical review on the clinical use of esophageal manometry. // Gastroenterology. -1994. -Vol.107. - P.1865-1884.
6. DeMeester T.R., Bonavina L., lascone C, et al. Chronic respiratory symptoms and occult gastroesophageal reflux: a prospective clinical study and results of surgical therapy. // Ann Surg. - 1990. - Vol.211. -P.337-45.
7. Ours T.M., Kavura M.S., Schilz R.J., et al. A prospective evaluation of esophageal testing and a double-blind, randomized study of omeprazole in a diagnostic and therapeutic algorithm for chronic cough// Am J. Gastroenterol. - 1999. -Vol.94. -P.3131-3138.
8. Fouad Y.M., Katz P.O., Hatlebakk J.G., et al. Ineffective esophageal motility: the most common motility abnormality in patients with GERD-associated respiratory symptoms. // Am. J. Gastroenterol. -1999. -Vol.94. -P.1464-1467.
9. Knight R.E., Wells J.R., Parrish R.S. Esophageal dysmotility as an important co-factor in extraesophageal manifestations of gastroesophageal reflux. // Laryngoscope. - 2000. -Vol. 110.-P. 1462-1466.
10. Marchesani E, Cecarini L, Pela R., et al. Causes of chronic persistent cough in adult patients: the results of a systematic management protocol. // Monaldi. Arch. Chest. Dis. -1998. -Vol.53. -P.510-514.
11. McGarvey L.P.A., Heaney L.G., Lawson J.T., et al. Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol. // Thorax. - 1998. -Vol.53. -P.738-743.
12. Simpson G. Investigation and management of persistent dry cough. // Thorax. - 1999. -Vol.54. - P.469.
13. Lundell L.R, Dent J, Bennett J.R., et al. Endoscopic assessment of esophagitis: clinical and functional correlates and further validation of the Los Angeles classification. // Gut 1999. -Vol. 45.-P. 172-178.
14. Clinical measurement in Gastroenterology. The Oesophagus, vol.1. / Eds. by Evans D.F., Buckton G.K. - London, 1997.
15. Stendal C. Practical Guide to Gastrointestinal Function Testing. Medtronics Gastrointestinal. - 1997.
16. Ing A.J., Ngu M.C., Breslin A.B.X. Chronic persistent cough and gastro-oesophageal reflux. // Thorax. - 1991. -Vol.46. -P.479-483.
17. Irwin R.S., French C.L., Curley F.J., et al. Chronic cough due to gastroesophageal reflux: clinical, diagnostic, and patho-genetic aspects. // Chest. - 1993. - Vol.104. - P.1511-1517.
18. Kastelik J.A., Redington A.E., Aziz I, et al. Abnormal oesophageal motility in patients with chronic cough // Thorax. - 2003. -Vol.58. -P.699-702.
19. Irwin R.S., Corrao W.M., Pratter M.R. Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of specific therapy. // Am. Rev. Respir. Dis. 1981. -Vol.123. -P.413-417.
20. Irwin R.S., Curley F.J., French C.L. Chronic cough: the spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. // Am. Rev. Respir. Dis. - 1990. -Vol.141. -P.640-647.
21. O'Connell F, Thomas VE, Pride NB, et al. Capsaicin cough sensitivity decreases with successful treatment of chronic cough. //Am. J. Respir. Crit. Care Med. - 1994. -Vol.150. -P.374-380.
22. Ing A.J., Ngu M.C., Breslin A.B.X. Pathogenesis of chronic persistent cough associated with gastroesophageal reflux. // Am. J. Respir. Crit. Care. Med. - 1994. -Vol.149. -P. 160-167.
23. Patti M.G., Debas H.T., Pellegrini C.A. Esophageal manometry and 24-hour pH monitoring in the diagnosis of pulmonary aspiration secondary to gastroesophageal reflux. // Am. J. Surg. 1992. -Vol.163. -P.401-406.