Материал: Kaplan USMLE-1 (2013) - Anatomy

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Chapter 4 • Embryonic Period (Weeks 3-8)

Table 11-4-1. Germ Layer Derivatives

Ectoderm

Mesoderm

Surface ectoderm

Muscle

Epidermis

Smooth

Hair

Cardiac

Nails

Skeletal

 

Inner ear, external ear

Connective tissue

Enamel ofteeth

All serous membranes

Lens ofeye

Bone and cartilage

 

Anterior pituitary (Rathke's pouch)

Blood, lymph, cardiovascular

Parotid gland

organs

Anal canal below pectinate line

Adrenal cortex

 

Neuroectoderm

Gonads and internal reproductive

organs

Neural tube

 

Central nervous system

Spleen

 

Retina and optic nerve

Kidney and ureter

 

Pineal gland

Dura mater

Neurohypophysis

 

Astrocytes

 

Oligodendrocytes

 

Neural crest ectoderm

Notochord

Nucleus pulposus

Adrenal medulla

 

Ganglia

 

Sensory-Pseudounipolar

 

Neurons

 

Autonomic-Postganglionic

 

Neurons

 

Pigment cells

 

Schwann cells

 

Meninges

 

Pia and arachnoid mater

 

Pharyngeal arch cartilage

 

Odontoblasts

 

Parafollicular (C) cells

 

Aorticopulmonary septum

 

Endocardial cushions

 

Yolk sac derivatives:

 

Primordial germ cells

 

Early blood cells and blood vessels

Endoderm

Forms epithelial lining of:

GI track: foregut, midgut, and hindgut

Lower respiratory system: larynx, trachea, bronchi, and lung

Genitourinary system: urinary bladder, urethra, and lower vagina

Pharyngeal pouches:

•Auditory tube and middle ear

•Palatine tonsils

•Parathyroid glands

•Thymus

Forms parenchyma of:

•Liver

•Pancreas

•Submandibular and sublingual glands

•Follicles ofthyroid gland

M EDICAL 167

Section II • Early Embryology

ChapterSummary

•The critical events ofthe third week are gastrulation and early development ofthe nervous and cardiovascular systems. Gastrulation is the process which establishes 3 primary germ layers that derive from epiblast: ectoderm, mesoderm, and endoderm. Gastrulation begins with the development of the primitive streak and node. The adult derivatives of ectoderm, mesoderm, and endoderm are given in Table 11-4-1.

168 MEDICAL

SECTION

GrossAnatomy

Back and Autonomic Nervous System

1

VERTEBRAL COLUMN

Embryology

During week 4, sclerotome cells ofthe somites (mesoderm) migrate medially to surround the spinal cord and notochord. After proliferation ofthe caudal portion ofthe sclerotomes, the vertebrae are formed, each consisting ofthe caudal part of one sclerotome and the cephalic part ofthe next.

Vertebrae

The vertebral column is the central component ofthe axial skeleton which func­ tions in muscle attachments, movements, and articulations ofthe head and trunk.

•The vertebrae provide a flexible support system that transfers the weight of the body to the lower limbs and also provides protection for the spinal cord.

•The vertebral column (Figure III- 1-1) is composed of 32-33 vertebrae (7 cervical, 12 thoracic, 5 lumbar, and the fused 5 sacral, and 3-4 coccy­ geal), intervertebral disks, synovial articulations (zygapophyseal joints) and ligaments.

MEDICAL 171

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