Материал: part17

U.1.7 Routine Stereo Camera Examination​

A stereo optic disk examination is ordered for a patient with glaucoma. For this examination, the IOP does not need to be measured.​ The procedure includes:​

1.​Mydriasis using agent at time t​

2.​N stereo pictures (camera pictures right and left stereo picture simultaneously) of the optic disk region at the time t+s​

The result is a study with:​

a.​N right and N left stereo pictures. These include acquisition information, lighting context, agent and time stamps.​

i.​ One Stereometric Relationship SOP Instance, indicating that the above OP images should be used as stereo pairs.​

U.1.8 Relative Image Position Definitions​

Ophthalmic mapping usually occurs in the posterior region of the fundus, typically in the macula or the optic disc. However, this or​ other imaging may occur anywhere in the fundus. The mapping data has clinical relevance only in the context of its location in the​ fundus, so this must be appropriately defined. CID 4207 “Ophthalmic Image Position” codes and the ocular fundus locations they​ represent are defined by anatomical landmarks and are described using conventional anatomic references, e.g., superior, inferior,​ temporal, and nasal. Figure U.1.8-1 is a schematic representation of the fundus of the left eye, and provides additional clarification​ of the anatomic references used in the image location definitions. A schematic of the right eye is omitted since it is identical to the left​ eye, except horizontally reversed (Temporal→Nasal, Nasal→Temporal).​

The spatial precision of the following location definitions vary depending upon their specific reference. Any location that is described​ as "centered" is assumed to be positioned in the center of the referenced anatomy. However, the center of the macula can be defined​ visually with more precision than that of the disc or a lesion. The locations without a "center" reference are approximations of the​ general quadrant in which the image resides.​

Note​

An image < 15° angular subtend in the same position should be considered Lesion Centered.​

Following are general definitions used to understand the terminology used in the code definitions.​

•​Central zone - a circular region centered vertically on the macula and extending one disc diameter nasal to the nasal margin of the​ disc and four disc diameters temporal to the temporal margin of the disc.​

•​Equator - the border between the mid-periphery and periphery of the retinal and corresponding to a circle approximately coincident​ with the ampulae of the vortex veins​

•​Superior - any region that is located superiorly to a horizontal line bisecting the macula​

•​Inferior - any region that is located inferiorly to a horizontal line bisecting the macula​

•​Temporal - any region that is located temporally to a vertical line bisecting the macula​

•​Nasal - any region that is located nasally to a vertical line bisecting the macula​

•​Mid-periphery - A circular zone of the retina extending from the central zone to the equator​

•​Periphery - A zone of the retinal extending from the equator to the ora serrata.​

•​Ora Serrata - the most anterior extent and termination of the retina​

•​Lesion - any pathologic object of regard​

Figure U.1.8-1 illustrates anatomical representation of defined regions of the fundus of the left eye according to anatomical markers.​ Therighteyehasthesamerepresentationsbutreversedhorizontallysothattemporalandnasalarereversedwiththemacularemaining​ temporal to the disc.​

Modified after Welch Allyn: http://www.welchallyn.com/wafor/students/Optometry-Students/BIO-Tutorial/BIO-Observation.htm.​

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Figure U.1.8-1. Anatomical Landmarks and References of the Left Ocular Fundus​

U.2 Typical Sequence of Events​

The following shows the proposed sequence of events using individual images that are captured for later stereo viewing, with the​ stereo viewing relationships captured in the stereometric relationship instance.​

B:OP SOP Instances stored for BOTH eyes

L:OP SOP Instances stored for LEFT eye

R:OP SOP Instances stored for RIGHT eye

Figure U.2-1. Typical Sequence of Events​

The instances captured are all time stamped so that the fluorescein progress can be measured accurately. The acquisition and​ equipment information captures the different setups that are in use:​

a.​Acquisition information A is the ordinary illumination and planned lenses for the examination.​

b.​Acquisition information B is the filtered illumination, filtered viewing, and lenses appropriate for the fluorescein examination.​

c.​Acquisition information C indicates no change to the equipment settings, but once the injection is made, the subsequent images​ include the drug, method, dose, and time of delivery.​

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U.3 Ophthalmic Tomography Use Cases (Informative)​

Optical tomography uses the back scattering of light to provide cross-sectional images of ocular structures. Visible (or near-visible)​ lightworkswellforimagingtheeyebecausemanyimportantstructuresareopticallytransparent(cornea,aqueoushumor,lens,vitreous​ humor, and retina - see Figure U.3-1).​

Figure U.3-1. Schematic representation of the human eye​

To provide analogy to ultrasound imaging, the terms A-scan and B-scan are used to describe optical tomography images. In this​ setting,anA-scanistheimageacquiredbypassingasinglebeamoflightthroughthestructureofinterest.AnA-scanimagerepresents​ the optical reflectivity of the imaged tissue along the path of that beam - a one-dimensional view through the structure. A B-scan is​ then created from a collection of adjacent A-scan images - a two dimensional image. It is also possible to combine multiple B-scans​ into a 3-dimensional image of the tissue.​

When using optical tomography in the eye it is desirable to have information about the anatomic and physiologic state of the eye.​ Measurementslikethepatient'srefractiveerrorandaxialeyelengtharefrequentlyimportantforcalculatingmagnificationorminification​ of images. The accommodative state and application of pupil dilating medications are important when imaging the anterior segment​ of the eye as they each cause shifts in the relative positions of ocular structures. The use of dilating medications is also relevant when​ imaging posterior segment structures because a small pupil can account for poor image quality.​

U.3.1 Anterior Chamber Tomography​

U.3.1.1 Anterior Chamber Exam For Phakic Intraocular Lens Surgery Planning​

Ophthalmic tomography may be used to plan placement of a phakic intraocular lens (IOL). A phakic IOL is a synthetic lens placed in​ the anterior segment of the eye in someone who still has their natural crystalline lens (i.e., they are "phakic"). This procedure is done​ to correct the patient's refractive error, typically a high degree of myopia (near-sightedness). The exam will typically be performed on​ both eyes, and each eye may be examined in a relaxed and accommodated state. Refractive information for each eye is required to​ interpret the tomographic study.​

A study consists of one or more B-scans (see Figure U.3-2) and one or more instances of refractive state information. There may be​ a reference image of the eye associated with each B-scan that shows the position of the scan on the eye.​

U.3.1.2 Anterior Chamber Angle Exam​

The anterior chamber angle is defined by the angle between the iris and cornea where they meet the sclera. This anatomic feature​ is important in people with narrow angles. Since the drainage of aqueous humor occurs in the angle, a significantly narrow angle can​ impede outflow and result in increased intraocular pressure. Chronically elevated intraocular pressures can result in glaucoma.​ Ophthalmic tomography represents one way of assessing the anterior chamber angle.​

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B-scans are obtained of the anterior segment including the cornea and iris. Scans may be taken at multiple angles in each eye (see​ Figure U.3-2). A reference image may be acquired at the time of each B-scan(s). Accommodative and refractive state information are​ also important for interpretation of the resulting tomographic information.​

Figure U.3-2. Tomography of the anterior segment showing a cross section through the cornea​

Note in the Figure the ability to characterize the narrow angle between the iris and peripheral cornea.​

U.3.1.4 Corneal Exam​

Asatransparentstructurelocatedatthefrontoftheeye,thecorneaisideallysuitedtoopticaltomography.Therearemultipledisease​ states including glaucoma and corneal edema where the thickness of the cornea is relevant and tomography can provide this inform-​ ation using one or more B-scans taken at different angles relative to an axis through the center of the cornea.​

Tomography is also useful for defining the curvature of the cornea. Accurate measurements of the anterior and posterior curvatures​ are important in diseases like keratoconus (where the cornea "bulges" abnormally) and in the correction of refractive error via surgery​ or contact lenses. Measurements of corneal curvature can be derived from multiple B-scans taken at different angles through the​ center of the cornea.​

In both cases, a photograph of the imaged structure may be associated with each B-scan image.​

U.3.2 Posterior Segment Tomography​

U.3.2.1 Retinal Nerve Fiber Layer Exam​

The Retinal Nerve Fiber Layer (RNFL) is made up of the axons of the ganglion cells of the retina. These axons exit the eye as the​ optic nerve carrying visual signals to the brain. RNFL thinning is a sign of glaucoma and other optic nerve diseases.​

Anophthalmictomographystudycontainsoneormorecircularscans,perhapsatvaryingdistancesfromtheopticnerve.Eachcircular​ scan can be "unfolded" and treated as a B-scan used to assess the thickness of the nerve fiber layer (see Figure U.3-3). A fundus​ image that shows the scan location on the retina may be associated with each B-scan. To detect a loss of retinal nerve fiber cells the​ exam might be repeated one or multiple times over some period of time. The change in thickness of the nerve fiber tissue or a trend​ (serial plot of thickness data) might be used to support the diagnosis.​

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Figure U.3-3. Example tomogram of the retinal nerve fiber layer with a corresponding fundus image​

In the Figure, the pseudo-colored image on the left shows the various layers of the retina in cross section with the nerve fiber layer​ between the two white lines. The location of the scan is indicated by the bright circle in the photograph on the right.​

U.3.2.2 Macular Exam​

The macula is located roughly in the center of the retina, temporal to the optic nerve. It is a small and highly sensitive part of the retina​ responsible for detailed central vision. Many common ophthalmic diseases affect the macula, frequently impacting the thickness of​ different layers in the macula. A series of scans through the macula can be used to assess those layers (see Figure U.3-4).​

A study may contain a series of B-scans. A fundus image showing the scan location(s) on the retina may be associated with one or​ more B-scans. In the Figure, the corresponding fundus photograph is in the upper left.​

Figure U.3-4. Example of a macular scan showing a series of B-scans collected at six different angles​

U.3.2.3 Angiographic Exams​

Some color retinal imaging studies are done to determine vascular caliber of retinal vessels, which can vary throughout the cardiac​ cycle.ImagesarecapturedwhileconnectedtoanECGmachineoracardiacpulsemonitorallowingimageacquisitiontobesynchronized​ to the cardiac cycle.​

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