Материал: Oxford American Handbook of Urology ( PDFDrive )

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xi

Detailed contents

1Significance and preliminary investigation of

urological symptoms and signs

1

Hematuria I: definition and types

2

 

Hematuria II: causes and investigation

4

Hematospermia 8

 

 

Lower urinary tract symptoms (LUTS)

10

Nocturia and nocturnal polyuria

14

 

Flank pain 16

 

 

Urinary incontinence in adults 20

 

Genital symptoms 22

 

 

Abdominal examination in urological disease 24

Digital rectal examination (DRE)

28

 

Lumps in the groin 30

 

 

Lumps in the scrotum 32

 

 

 

 

 

2

Urological investigations

35

 

Urine examination 36

 

 

Urine cytology 38

 

 

Prostatic specific antigen (PSA)

39

 

Radiological imaging of the urinary tract 40

 

Uses of plain abdominal radiography (KUB X-ray—kidneys,

 

ureters, bladder) 42

 

 

Intravenous pyelography (IVP)

44

 

Other urological contrast studies 48

 

Computed tomography (CT) and magnetic resonance

 

imaging (MRI) 50

 

 

Radioisotope imaging 52

 

 

Uroflowmetry 54

 

 

Post-void residual urine volume measurement 58

 

Cystometry, pressure-flow studies, and videocystometry 60

 

 

 

3

Bladder outlet obstruction

63

 

Regulation of prostate growth and development of benign

 

prostatic hyperplasia (BPH) 64

 

 

Pathophysiology and causes of bladder outlet obstruction

 

 

(BOO) and BPH 66

 

 

Benign prostatic obstruction (BPO): symptoms and signs

68

xii

 

DETAILED CONTENTS

 

 

 

 

 

 

Diagnostic tests in men with LUTS thought to be due to

 

 

 

BPH 70

 

 

 

 

 

 

Why do men seek treatment for their symptoms? 72

 

 

 

 

Watchful waiting for uncomplicated BPH

74

 

 

 

 

Medical management of BPH: A-blockers

76

 

 

 

 

Medical management of BPH: 5A-reductase inhibitors

78

 

 

 

Medical management of BPH: combination therapy 80

 

 

 

 

Medical management of BPH: alternative drug therapy

82

 

 

 

Minimally invasive management of BPH: surgical alternatives

 

 

to TURP 84

 

 

 

 

 

 

Invasive surgical alternatives to TURP 86

 

 

 

 

 

TURP and open prostatectomy 88

 

 

 

 

 

Acute urinary retention: definition, pathophysiology, and

 

 

 

causes 90

 

 

 

 

 

 

Acute urinary retention: initial and definitive management

94

 

 

Indications for and technique of urethral catheterization 96

 

 

Indications for and technique of suprapubic catheterization

98

 

 

Management of nocturia and nocturnal polyuria 100

 

 

 

 

High-pressure chronic retention (HPCR)

102

 

 

 

 

Bladder outlet obstruction and retention in women 104

 

 

 

Urethral stricture disease 106

 

 

 

 

 

 

 

 

 

 

 

4

Incontinence

 

 

 

109

 

 

Classification 110

 

 

 

 

 

 

Causes and pathophysiology 112

 

 

 

 

 

 

Evaluation 114

 

 

 

 

 

 

Treatment of sphincter weakness incontinence: injection

 

 

 

therapy 116

 

 

 

 

 

 

Treatment of sphincter weakness incontinence: retropubic

 

 

 

suspension 117

 

 

 

 

 

 

Treatment of sphincter weakness incontinence: pubovaginal

 

 

slings 118

 

 

 

 

 

 

Treatment of sphincter weakness incontinence: the artificial

 

 

urinary sphincter 120

 

 

 

 

 

 

Overactive bladder: conventional treatment 122

 

 

 

 

Overactive bladder: options for failed conventional

 

 

 

 

therapy 124

 

 

 

 

 

 

“Mixed” incontinence 126

 

 

 

 

 

 

Post-prostatectomy incontinence

128

 

 

 

 

 

Vesicovaginal fistula (VVF) 130

 

 

 

 

 

 

Incontinence in the elderly patient

132

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

DETAILED CONTENTS

xiii

5

Infections and inflammatory conditions

133

 

 

Urinary tract infection: definitions, incidence, and

 

 

 

investigations 134

 

 

 

 

 

 

Urinary tract infection: microbiology 138

 

 

 

Lower urinary tract infection 140

 

 

 

Recurrent urinary tract infection

142

 

 

 

Urinary tract infection: treatment

146

 

 

 

Acute pyelonephritis 148

 

 

 

 

Pyonephrosis and perinephric abscess 150

 

 

 

Other forms of pyelonephritis 152

 

 

 

Chronic pyelonephritis

154

 

 

 

 

Septicemia and urosepsis

156

 

 

 

 

Fournier gangrene

160

 

 

 

 

 

 

Epididymitis and orchitis

162

 

 

 

 

Periurethral abscess 164

 

 

 

 

 

Prostatitis: epidemiology and classification 166

 

 

 

Prostatitis: presentation, evaluation, and treatment 168

 

 

 

Other prostate infections

170

 

 

 

 

Interstitial cystitis

172

 

 

 

 

 

 

Tuberculosis 176

 

 

 

 

 

 

 

Parasitic infections

178

 

 

 

 

 

 

HIV in urological surgery

180

 

 

 

 

Inflammatory and other disorders of the penis 182

 

 

 

 

 

 

 

 

 

6

Urological neoplasia

 

 

 

185

 

 

Pathology and molecular biology

188

 

 

 

Prostate cancer: epidemiology and etiology 190

 

 

 

Prostate cancer: incidence, prevalence, and mortality 192

 

Prostate cancer pathology: premalignant lesions 193

 

 

 

Prostatic-specific antigen (PSA) and prostate cancer

 

 

 

screening 194

 

 

 

 

 

 

 

Counseling before prostate cancer screening 195

 

 

 

Prostate cancer: clinical presentation 196

 

 

 

PSA and prostate cancer

198

 

 

 

 

PSA derivatives: free-to-total ratio, density, and velocity

200

 

 

Prostate cancer: transrectal ultrasonography and

 

 

 

biopsies 202

 

 

 

 

 

 

 

Prostate cancer staging

206

 

 

 

 

Prostate cancer grading

212

 

 

 

xiv DETAILED CONTENTS

Risk stratification in management of prostate cancer 214

General principles of management of localized prostate cancer 215

Management of localized prostate cancer: watchful waiting and active surveillance 216

Management of localized prostate cancer: radical prostatectomy 218

Postoperative course after radical prostatectomy 222 Prostate cancer control with radical prostatectomy 224

Management of localized prostate cancer: radical external beam radiotherapy (EBRT) 226

Management of localized prostate cancer: brachytherapy (BT) 228

Management of localized and radiorecurrent prostate cancer: cryotherapy and HIFU 230

Management of locally advanced nonmetastatic prostate cancer (T3–4 N0M0) 232

Management of advanced prostate cancer: hormone therapy I 233

Management of advanced prostate cancer: hormone therapy II 234

Management of advanced prostate cancer: hormone therapy III 238

Management of advanced prostate cancer: androgen-independent/ castration-resistant disease 240

Palliative management of prostate cancer 242

Prostate cancer: prevention; complementary and alternative therapies 244

Bladder cancer: epidemiology and etiology 246 Bladder cancer: pathology and staging 248 Bladder cancer: presentation 252

Bladder cancer: diagnosis and staging 254

Management of superficial UC: transurethral resection of bladder tumor (TURBT) 256

Management of superficial UC: adjuvant intravesical chemotherapy and BCG 258

Muscle-invasive bladder cancer: surgical management of localized (pT2/3a) disease 260

Muscle-invasive bladder cancer: radical and palliative radiotherapy 263

Muscle-invasive bladder cancer: management of locally advanced and metastatic disease 264

Bladder cancer: urinary diversion after cystectomy 266

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